Cajun Baked Salmon

Juicy, flaky Cajun baked salmon coated in bold Cajun seasoning and baked with tender bell peppers, onions, and garlic for an easy, flavor-packed dinner. This simple one-pan salmon recipe is ready in about 30 minutes. Serve it over rice, quinoa, or alongside roasted vegetables.
5 from 7 votes
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5 stars

Easy and quick with a nice kick. I make it with wild caught salmon to ensure best results. Thanks for the recipe! ~Rachel

Seasoned Cajun Salmon with onion and peppers baked in a cast iron pan.

Quick Look at This Cajun Baked Salmon

Prep Time: 10 minutes
🔥 Cook Time: 20–25 minutes
🍽 Servings: 4
🔥 Calories: ~458 per serving
🌶 Flavor: Bold, smoky, slightly spicy Cajun seasoning with sweet roasted peppers
🐟 Texture: Juicy, flaky salmon with tender roasted vegetables
👩‍🍳 Difficulty: Easy (perfect for beginners!)
🍳 Cooking Method: Oven-baked, one pan
🥗 Diet: Gluten-free, high-protein, low-carb friendly
💡 Best For: Quick weeknight dinners or healthy meal prep

👉 Bonus: This is a complete one-pan meal with protein and veggies baked together, so cleanup is minimal!

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Why You’ll Love My Easy Cajun Salmon

Quick and easy (ready in about 30 minutes): salmon is a great protein for weeknight or weekend easy dinners. It cooks fast, juicy, moist, and convenient.

One-pan meal, less cleanup: I cook the fish and the veggies in one skillet, so unless you need an extra side, it’s all done in one pan.

Packed with bold Cajun flavor: It brings smoky, spicy, and slightly savory flavor and often combines: paprika, cayenne pepper, garlic powder, onion powder, black pepper, white pepper, oregano, thyme, and salt.

Naturally gluten-free and healthy: my recipe is naturally gluten free as followed, if you use store-bought seasoning, check the packaging! Salmon is a great protein with lots of health benefits.

Ingredients You’ll Need (and Why They Matter)

Here’s a quick breakdown so your readers understand why each ingredient is important:

  • Salmon fillets (skin-on) – Skin helps protect the fish from drying out and keeps it juicy while baking. It also adds extra flavor from the natural fats.
  • Cajun seasoning – check the label of the Cajun seasoning to make sure it fits your needs with salt content and possible gluten content. It brings smoky, spicy, and slightly savory flavor. (Tip: salt levels vary by brand, so always taste first.)
  • Oil – Helps the seasoning stick and keeps the salmon moist while baking. Use a good-quality, neutral oil, like avocado oil, to avoid bitterness.
  • Veggies Bell peppers & Red onion: classic vegetables is Cajun cooking and provide a nice balance of sweetness to the spice. Feel free to add others (see FAQs below.)
  • Garlic – for best flavor, use fresh garlic that you peel, smash, and mince. This brings out the most flavor and aroma. If needed, pre-minced garlic works but flavor is quite different.

How To Make Cajun Salmon

This is a very simple, minimum effort dish that tastes fantastic. Since it’s mostly hands-off recipe, it’s perfect for weeknights:

seasoned sliced red onions and red and orange bell peppers in a metal mixing bowl.

Step 1: Preheat your oven to 425°F.

Step 2: Prepare the vegetables: Slice the bell peppers, onion, and garlic. Toss them with oil and Cajun seasoning. This ensures the veggies roast evenly and absorb flavor.

Step 3: Season the salmon: Pat salmon dry and rub it with olive oil, then coat evenly with Cajun seasoning.

PRO Tip: Drying the salmon first gets rid of excess moisture and helps the seasoning stick better.

Cajun salmon coated in seasoning, uncooked with seasoned onions and peppers in a skillet.

Step 4: Assemble the pan: Lightly oil a large skillet or baking dish. Place salmon skin-side down and spread veggies around it.

Step 5: Bake: Bake for 20-25 minutes, depending on thickness. You can check salmon by touch or use a meat thermometer. It is recommended by USDA to cook salmon to 145°F internal temperature, which is when salmon is considered fully done. Personally, I prefer salmon at either medium or medium-well temperature, which is around 125°F-130°F.

juicy baked Cajun salmon over bell peppers and onions on a white plate.

Helpful Tips for the Best Salmon

I cook salmon at least once a week because that is my absolute favorite fish and one of my favorite proteins. I’ve learned so much about it and here are my top tips:

  • Don’t overcook! This is the #1 mistake that leads to dry salmon. I recommend medium to medium-well salmon temperature for the best moist and juicy salmon.
  • Use skin-on salmon for better moisture and flavor. It really does help keep salmon moist and flavorful and you can always take the skin off before serving.
  • Cut veggies evenly so they cook at the same rate.
  • Use a meat thermometer for perfect doneness unless you have a lot of experience in cooking fish and can tell by touch.

Best Way To Store and Reheat Baked Salmon

  • Storage: Store leftovers in an airtight container in the refrigerator for up to 3 days.
  • Reheating: Reheat gently in the oven at 275°F for 13-16 minutes to prevent drying out. Cover loosely with foil to keep moisture in.
  • No Reheat Idea (Great Tip!): Cold salmon is delicious in salads, grain bowls, avocado toast, egg sandwiches.
Flavorful Cajun Salmon on a plate with onions and peppers and using a fork to flake apart juicy meat.

Cajun Baked Salmon FAQs

Why cook salmon with skin on?

Even if you don’t eat the skin, keep it on while cooking because: it protects the fish from drying out, helps prevent sticking, adds flavor from natural fats, and locks in moisture.
 

What other veggies can I add?

You can increase the amount of veggies but make sure to use a larger size pan or a larger baking dish. Some good veggies to add include mushrooms, asparagus, green beans, sliced carrots, broccoli, cauliflower, and corn.

Can I use frozen salmon?

Yes! Just make sure to thaw it completely in the refrigerator overnight and pat dry before seasoning.

Is Cajun salmon spicy?

It can be! Taste your Cajun seasoning first and if it needs more salt or spice adjust accordingly. If it has too much spice, add a pinch of sugar to balance it out and use less of it. Just don’t forget the salt.

SOME MORE FISH RECIPES TO TRY:

If you love easy salmon dinners, make sure to also try my Baked Salmon and Asparagus dish, Salmon Florentine and don’t miss a simple 4-Ingredient Orange Salmon. Learn how to make Crispy Skin Salmon as an alternative to baked salmon. Use you leftover salmon is some Salmon Tacos.

DID YOU MAKE THIS RECIPE? PLEASE leave a 🌟 star rating! Let me know how you liked it by leaving the 📝 comment below or share and tag me on social media @willcookforsmiles. DON’T FORGET to subscribe to my newsletter!

Cajun Baked Salmon Recipe

Juicy, flaky Cajun baked salmon coated in bold Cajun seasoning and baked with tender bell peppers, onions, and garlic for an easy, flavor-packed dinner. This simple one-pan salmon recipe is ready in about 30 minutes. Serve it over rice, quinoa, or alongside roasted vegetables.
5 from 7 votes
Print Pin Video Rate
Course: dinner, Main Course
Cuisine: American, Cajun
Diet: Gluten Free, Low Fat
Prep Time: 10 minutes
Cook Time: 22 minutes
Total Time: 32 minutes
Servings: 4
Calories: 458kcal
Author: Lyuba Brooke

Ingredients

  • 2 lbs salmon fillets
  • 1 1/2-2 tbsp Cajun seasoning for salmon
  • 3 tbsp avocado or olive oil divided
  • 2 tsp Cajun seasoning for veggies
  • 2 large bell peppers
  • 1 red onion
  • 3 garlic cloves smashed and minced
  • salt** (may or may not be needed depending on Cajun seasoning mix)

Instructions

  • Preheat oven to 425°F.
  • Rub some oil over the bottom of a large cast iron skillet. (You can also use a baking dish wide enough to fit salmon and veggies.)
  • Slice peppers and onion, smash and mince the garlic. Mix veggies with Cajun seasoning and half of the oil. 
  • Rub salmon pieces with remaining oil and then sprinkle Cajun seasoning all over. 
  • *Tip: taste your Cajun seasoning mix before using it to check if more salt is needed. If needed, add a little salt to salmon and veggies.
  • Place salmon skin down in the skillet and spread veggies all around it. 
  • Bake for 20-25 minutes, depending on the thickness of salmon. 
  • You can check salmon by touch or use a meat thermometer. It is recommended by USDA to cook salmon to 145°F internal temperature, which is when salmon is considered fully done. Personally, I prefer salmon at either medium or medium-well temperature, which is around 125°F-130°F.

Video

Notes

Oil tip: make sure your oil is good quality and neutral in flavor, so it has no bitterness to it or it will transfer into your dish.
 

Nutrition

Calories: 458kcal | Carbohydrates: 8g | Protein: 46g | Fat: 25g | Saturated Fat: 3g | Cholesterol: 124mg | Sodium: 106mg | Potassium: 1370mg | Fiber: 3g | Sugar: 4g | Vitamin A: 3775IU | Vitamin C: 78.7mg | Calcium: 50mg | Iron: 3mg
Tried this recipe?Mention @willcookforsmiles or tag #willcookforsmiles!

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All images and text ©Lyubov Brooke for ©Will Cook For Smiles. Please do not use my images without prior permission. If using my posts in collections and features, please link back to this post for the recipe.
Disclaimer: Nutrition information shown is not guaranteed to be 100% accurate as most ingredients and brands have variations.

5 from 7 votes (3 ratings without comment)

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10 Comments

  1. 5 stars
    Easy and quick with a nice kick. I make it with wild caught salmon to ensure best results. Thanks for the recipe!

    1. SO glad you liked it, Rachel!

  2. Catherine Harris says:

    5 stars
    Cajun baked Salmon🍣 is so delicious 😋 ! I love the mixed chopped veggies to go with it! I’m cooking this tomorrow night 4dinner 4my family of four! I’m also cooking some Knorr Chicken Flavored Rice 🍚 with it and Garlic Bread 🍞 on da side! I believe it would be a great healthy meal for us all 2enjoy 😉! Thanks for your twist on this ! I love it!

    1. Thank you, Catherine! I hope you enjoy the recipe!

  3. 5 stars
    Marvellous recipe. So simple, tasty and healthy!

  4. Greg Divine says:

    5 stars
    I made this recipe tonight and I and the family loved it ! Peppers, onion and Salmon seemed like it would be a home run and it was . I’ve loved Salmon since the first time I had as a kid on Kodak Island in Alaska. I will absolutely be making this recipe many more times for sure . Thank you so much for sharing your recipe with us.

    1. I am so glad you liked it, Greg!

  5. Sharon Worley says:

    What Cajun seasoning do you like to use?

  6. I just saw your Cajun Baked Salmon recipe & would like to try a variation, as I don’t like bell peppers. I love the idea of the cajun seasoning, onions, etc. Any thoughts about what other veggies might work?

    1. I’m so sorry for the late response! I think you could use zucchini and summer squash or green beans and asparagus. I bet that would be just as delicious. Hope that helps!

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